Dependence & Withdrawal
Opioid-like dependence and severe withdrawal requiring treatment with medications like buprenorphine and methadone.
Learn More →Whole‑Leaf Kratom · Not Just Synthetics
Banning 7‑OH Alone Won't Protect Families.
Natural Kratom Causes Real Harm.
This library compiles peer‑reviewed evidence, FDA reports, and CDC case studies documenting the dangers of unregulated whole‑leaf kratom – dependence, withdrawal, liver injury, cardiac arrest, and deaths.
MISSION
We advocate for evidence‑based policy that protects public health, informs lawmakers, and prevents harm from unregulated kratom – including natural whole leaf products, not just high‑potency extracts.
Natural Leaf vs Extracts:
What Policymakers Should Know
Even before high‑potency 7‑OH extracts emerged, whole‑leaf kratom was associated with severe outcomes, contamination, and healthcare burden. Understanding the full market matters for effective regulation.
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"The FDA didn't ban it!"
Despite decades of documented harms, whole‑leaf kratom remains unregulated. Learn why federal action has stalled – and what can still be done.
Learn More →KEY PUBLIC HEALTH INDICATORS
Federal and poison-center surveillance signals
Data from national systems tracking kratom-related harms, exposures, and adverse events.
CDC SUDORS
1,151
Kratom/mitragynine detected in overdose deaths in 2023 across participating jurisdictions.
2020–2024 range: 866 to 1,151 annual detections
AMERICA'S POISON CENTERS
14,449
Poison center exposure reports involving kratom from 2011–2023.
National Poison Data System surveillance
FDA FAERS
1,470
FAERS adverse-event reports associated with kratom/mitragynine.
Includes 722 death outcomes and 370 hospitalizations
The Issues
Scientific evidence shows significant public health risks from whole‑leaf kratom and its alkaloids.
Cardiac Toxicity
Reports of Brugada syndrome, QT prolongation, arrhythmias, cardiac arrest, and sudden death in healthy individuals.
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Liver Injury
Cases of cholestatic injury, liver failure, and transplant linked to kratom use. Recovery often occurs after cessation (NIH LiverTox).
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Pregnancy & Neonatal Risk
Evidence of neonatal withdrawal, limited safety data, and potential harm to developing infants.
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Youth & College Exposure
Increasing use among adolescents and college students fueled by aggressive marketing and easy access.
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Product Contamination
Heavy metals, microbes, pesticides, adulterants, and variable potency found in many products (FDA lab data).
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For Lawmakers:
Better Policy Saves Lives
Outdated laws and lack of enforcement leave families vulnerable. We provide the data, documents, and expert analysis needed to protect communities. (State Laws Summary)
Resources for Lawmakers →Latest News
View All News →
Policy
States Move to Protect Families as Kratom-Related Harms Rise
May 8, 2026
User Reports
Does Pure Leaf Kratom Get You High? A Review of Reddit User Reports
June 6, 2026
Clinical Trial
Does Pure Leaf Kratom Get You High? Part II – The FDA-Sponsored Human Trial
June 29, 2026
Regulation
Florida Raises 7‑OH Limit 2.5× Despite Declaring "Imminent Hazard"
June 25, 2026
Policy Analysis
Pinney's Plan. DEA's Policy. – How an Industry-Linked Strategy Became Federal Policy
July 9, 2026
Policy Analysis
Connecticut Consumer Accounts Reveal Severe Whole‑Leaf Kratom Dependence
July 17, 2026
We are mothers, families, clinicians, and concerned citizens united to end preventable harm.Whole‑leaf kratom is not a harmless botanical. Real oversight, testing, and enforcement can save lives.